oleanolic acid CAS#:508-02-1_上海皓元生物医药科技有限公司

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oleanolic acid

CAS号	508-02-1
规格	100mg500mg	纯度	98%
货号	HY-N0156	货期	3天
品牌	Medchemexpress	库存	需咨询
规格	100mg500mg
纯度	98%
货号	HY-N0156
货期	3天
品牌	Medchemexpress
库存	---
注意：请务必与卖家联系核实单价库存，以确保您的资金安全及交易顺利。
参考价：￥380.00 元/100mg

立即询盘

货号	品牌	纯度	规格	参考价	货期
HY-N0156	Medchemexpress	98%	100mg500mg	￥380.00元/100mg	3天

产品详情

详细信息(中文)：
齐墩果酸(Oleanolic Acid)是一具有抗癌活性的天然化合物。

详细信息(英文)：
产品描述：Oleanolic AcidOleanolic acid (Caryophyllin) is a natural compound from plants with anti-tumor activities._x000D_ IC50 value:_x000D_ Target:_x000D_ in vitro: OA suppressed the proliferation of lung cancer cells in both dose- and time-dependent manners, along with an increase in miR-122 abundance. The suppression of miR-122 abolished the effect of OA on lung cancer cells. CCNG1 and MEF2D, two putative miR-122 targets, were found to be downregulated by OA treatment [1]. OA induced autophagy in normal tissue-derived cells without cytotoxicity. OA-induced autophagy was shown to decrease the proliferation of KRAS-transformed normal cells and to impair their invasion and anchorage-independent growth [2]._x000D_ in vivo: Mouse model experiments also demonstrated that OA suppressed the growth of KRAS-transformed breast epithelial cell MCF10A-derived tumor xenograft by inducing autophagy [2]. activation of MAPK pathways, including p-38 MAPK, JNK and ERK, was triggered by OA in both a dose and time-dependent fashion in all the teste 公司介绍：MedChemExpress(MCE)专注于各种抑制剂、激动剂、API及化合物库，总部位于美国新泽西，分别在瑞典和上海设有欧洲区子公司和亚洲区总代理，营销网点遍及全球20多个国家地区。MCE经过多年努力已成为全球生物活性小分子领域的一流供应商，产品涵盖癌症、神经科学、抗感染、表观遗传学等20个热门研究领域，PI3K、MAPK等近千个细分靶点，超过4000个活性小分子化合物现货，以及GPCR、API、离子通道等超过20种不同类型的化合物库，同时提供从毫克到千克的专业定制合成服务。 MCE 对每批产品都进行严格的LCMS和NMR检验，其产品已被全球近万名客户广泛使用并发表大量文章、专利； MCE 定期增加各领域热门抑制剂、激动剂，不断扩增已有化合物库，以满足最新的科研需求；数千种产品在上海有充足备货，24-48小时内送达客户；大量产品提供免费试用装；已为全球多个知名企业、院校构建各种定制型化合物库。产品链接：www.medchemexpress.cn/oleanolic-acid.html