Deflazacort CAS#:14484-47-0_上海皓元生物医药科技有限公司

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Deflazacort

CAS号	14484-47-0
规格	50mg100mg	纯度	98%
货号	HY-13609	货期	3天
品牌	Medchemexpress	库存	需咨询
规格	50mg100mg
纯度	98%
货号	HY-13609
货期	3天
品牌	Medchemexpress
库存	---
注意：请务必与卖家联系核实单价库存，以确保您的资金安全及交易顺利。
参考价：￥714.00 元/50mg

立即询盘

货号	品牌	纯度	规格	参考价	货期
HY-13609	Medchemexpress	98%	50mg100mg	￥714.00元/50mg	3天

产品详情

详细信息(中文)：
Deflazacort为糖皮质素，可作为抗炎剂和免疫抑制剂。

详细信息(英文)：
产品描述：DeflazacortDeflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant._x000D_ Target: Glucocorticoid Receptor_x000D_ Deflazacort is an inactive prodrug which is converted rapidly to the active metabolite 21-desacetyldeflazacort. Maximum concentrations of 21-desacetyldeflazacort averaged 116 ng/ml and were observed after 1.3 h. The average area under the curve was 280 ng/ml.h, and the terminal half-life was 1.3 h. 21-Desacetyldeflazacort was cleared significantly faster than both methylprednisolone and prednisolone [1]. Two of 40 boys treated with deflazacort died at 13 and 18 years of age from cardiac failure. The treated boys were significantly shorter, did not have excessive weight gain and 22 of 40 had asymptomatic cataracts. Deflazacort has a very significant impact on health, quality of life and health care costs for boys with DMD and their families, and is associated with few side effects [2]._x000D_ 公司介绍：MedChemExpress(MCE)专注于各种抑制剂、激动剂、API及化合物库，总部位于美国新泽西，分别在瑞典和上海设有欧洲区子公司和亚洲区总代理，营销网点遍及全球20多个国家地区。MCE经过多年努力已成为全球生物活性小分子领域的一流供应商，产品涵盖癌症、神经科学、抗感染、表观遗传学等20个热门研究领域，PI3K、MAPK等近千个细分靶点，超过4000个活性小分子化合物现货，以及GPCR、API、离子通道等超过20种不同类型的化合物库，同时提供从毫克到千克的专业定制合成服务。 MCE 对每批产品都进行严格的LCMS和NMR检验，其产品已被全球近万名客户广泛使用并发表大量文章、专利； MCE 定期增加各领域热门抑制剂、激动剂，不断扩增已有化合物库，以满足最新的科研需求；数千种产品在上海有充足备货，24-48小时内送达客户；大量产品提供免费试用装；已为全球多个知名企业、院校构建各种定制型化合物库。产品链接：www.medchemexpress.cn/deflazacort.html